Synthesis of ortho-cyanopyridylboronic acids and esters toward cyano-functionalized bipyridines
Synthesis of ortho-cyanopyridylboronic acids and esters toward cyano-functionalized bipyridines
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DOI：
10.1055/s-2005-922772
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发表时间：
2006-01-05
期刊：
影响因子：
2
通讯作者：
Rault, S
中科院分区：
文献类型：
--
作者：
Cailly, T;Fabis, F;Rault, S
本文介绍了邻氰基吡啶基硼酸及其酯的合成。它们与吡啶卤化物的Suzuki交叉偶联反应的反应性进行了评价，并表明氰基吡啶硼酸酯似乎比它们相应的酸更稳定。这些酯使我们能够合成新的氰基联吡啶系统。
This work describes the synthesis of ortho-cyanopy-ridylboronic acids and esters. Their reactivity with pyridine halides in the Suzuki cross-coupling reaction is evaluated and shows that the cyanopyridyl boronic esters appear to be more stable than their corresponding acids. These esters allowed us to synthesize new cyanobipyridine systems.