Specific histone modification responds to arsenic-induced oxidative stress
Specific histone modification responds to arsenic-induced oxidative stress
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特定组蛋白修饰响应砷诱导的氧化应激
DOI：
10.1016/j.taap.2016.03.015
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发表时间：
2016-07-01
影响因子：
3.8
通讯作者：
Zhang, Aihua
中科院分区：
文献类型：
--
作者：
Ma, Lu;Li, Jun;Zhang, Aihua
为了探讨特定的组蛋白修饰是否与砷诱导的氧化损伤有关，我们招募了138名来自中国贵州省新仁县焦乐村的砷暴露和砷中毒受试者，那里的居民暴露于室内燃煤砷。上八田村77名未接触高砷煤的村民作为对照组。砷暴露组尿砷和发砷浓度分别为对照组的2.4倍和2.1倍（均P
To explore whether specific histone modifications are associated with arsenic-induced oxidative damage, we recruited 138 arsenic-exposed and arsenicosis subjects from Jiaole Village, Xinren County of Guizhou province, China where the residents were exposed to arsenic from indoor coal burning. 77 villagers from Shang Batian Village that were not exposed to high arsenic coal served as the control group. The concentrations of urine and hair arsenic in the arsenic-exposure group were 2.4-fold and 2.1-fold (all P