Perinatal factors and the risk of testicular germ cell tumors
Perinatal factors and the risk of testicular germ cell tumors
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DOI：
10.1002/ijc.23424
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发表时间：
2008-06-01
影响因子：
6.4
通讯作者：
McGlynn, Katherine A.
中科院分区：
文献类型：
--
作者：
Cook, Michael B.;Graubard, Barry I.;McGlynn, Katherine A.
Testicular germ cell tumors (TGCT) are the most common cancer among young men in the United States and Western Europe. Prior evidence suggests that TGCT may arise in perinatal life, although few risk factors have yet been identified. To study the etiology of TGCT, the US Servicemen's Testicular Tumor Environmental and Endocrine Determinants (STEED) case-control study enrolled participants and their mothers between 2002 and 2005. Five hundred twenty-seven mothers of cases and 561 mothers of controls provided information on perinatal variables. Logistic regression was used to calculate odds ratios (OR) and 95% confidence intervals (95%Cl) associated with the candidate risk factors. Analyses were conducted for all TGCT together and for each histologic subgroup (seminoma and nonseminoma) separately. Young maternal age (
