Calorimetric and Kinetic Analysis of Thermal Behaviors of Chrome-tanned Collagen Fibers Using Isoconversional and Multivariate Non-linear Regression Methods
Calorimetric and Kinetic Analysis of Thermal Behaviors of Chrome-tanned Collagen Fibers Using Isoconversional and Multivariate Non-linear Regression Methods
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使用等转换和多元非线性回归方法对铬鞣胶原纤维的热行为进行量热和动力学分析
DOI：
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发表时间：
2017
影响因子：
0.9
通讯作者：
Li Guoying
中科院分区：
文献类型：
--
作者：
Liu Wentao;Zhang Yuanzhi;Li Guoying
用DSC等温法观察大鼠尾腱胶原的热变性过程，并根据Arrhenius方程对温度有速率依赖性。很明显，胶原蛋白的热变性（或收缩）是一个动力学过程，因此单一的T d（或T s）值不能提供胶原蛋白热稳定性的准确估计。为了进一步了解真皮和皮革中胶原蛋白的热稳定性，采用非等温差示扫描量热法（DSC），采用等转换和多元非线性回归（Multivar-NLR）方法研究了铬鞣胶原纤维的热变性行为。微分（Friedman）和积分（Ozawa-Flynn-Wall）等转换方法以及Multivar-NLR方法表明，变性（或收缩）过程可以用三步模型来描述，其中可逆反应之后是速率有限的不可逆反应。对不同温度条件下胶原蛋白热行为的模拟表明，在低加热速率或温度下，变性动力学可近似为一步不可逆反应。为使胶原蛋白具有足够高的热稳定性，设计新的无铬鞣体系时，除了提高变性（或收缩）温度、焓和有效活化能外，降低胶原蛋白不可逆变性速率也可能是一个重要的标准。
thermal denaturation of collagen in rat tail tendon by using DSC isothermally, and there was an rate dependence on temperature obeying the Arrhenius equation. 8 It is obvious that the thermal denaturation (or shrinkage) of collagen is a kinetic process and thus a single value of T d (or T s ) could not provide an accurate estimate for the thermal stability of collagen. Moreover, both T d and T s are highly dependent on the heating rate which might be responsible for the difference between the values of T d Abstract To further understand the thermal stability of collagen in hide and leather, the thermal denaturation behaviors of chrome-tanned collagen fibers were studied by non-isothermal differential scanning calorimetry (DSC) using isoconversional and multivariate non-linear regression (Multivar-NLR) methods. The differential (Friedman) and the integral (Ozawa-Flynn-Wall) isoconversional methods as well as the Multivar-NLR method showed that the denaturation (or shrinkage) process could be best described by a three-step model, in which a reversible reaction was followed by a rate-limited irreversible step. The simulation of thermal behaviors of collagen at different temperature conditions indicated that the denaturation kinetics could be approximated to a one-step irreversible reaction at low heating rates or temperatures. For the design of new chrome-free tanning systems, which can endow collagen with high enough thermostability, the decrease in the rate of the irreversible denaturation of collagen might be an important criterion as well, besides the increases in the denaturation (or shrinkage) temperature, enthalpy and effective activation energy.
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影响因子：
4.4
作者：
Yajuan Wang;Jun Guo;Hui Chen;Z. Shan
通讯作者：
Yajuan Wang;Jun Guo;Hui Chen;Z. Shan
影响因子：
0.3
作者：
L. E. Richard
通讯作者：
L. E. Richard
基于铝锆复合鞣剂白湿鞣的反铬鞣技术
影响因子：
0.9
作者：
Cai Siwei;Zeng Yunhang;Zhang Wenhua;Wang Ya-nan;Shi Bi
通讯作者：
Shi Bi
DOI：
10.1016/s0945-053x(01)00137-8
发表时间：
2001-07
期刊：
Matrix biology : journal of the International Society for Matrix Biology
影响因子：
--
作者：
C. A. Miles;A. Bailey
通讯作者：
C. A. Miles;A. Bailey
DOI：
10.1016/j.ijbiomac.2017.04.124
发表时间：
2017-10
影响因子：
8.2
作者：
Michaela Schroepfer;M. Meyer
通讯作者：
Michaela Schroepfer;M. Meyer