Nitrogen cycle enzymology

Nitrogen cycle enzymology
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DOI:
10.1016/s1367-5931(98)80059-8
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发表时间:
1998-04-01
影响因子:
7.8
通讯作者:
Ferguson, SJ
Ferguson, SJ
中科院分区:
生物学2区
文献类型:
--
作者:
Ferguson, SJ

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最小氮循环涉及五个还原反应和三个氧化反应,每个反应都在生物无机化学、能量转导和蛋白质结构/功能关系中提出有趣的问题。该领域的许多重大最新进展都依赖于蛋白质晶体结构的获取,包括具有结合底物或产物的酶结构以及蛋白质-蛋白质复合物的结构。这些酶包括固氮酶、亚硝酸还原酶、羟胺氧化还原酶和真菌一氧化氮还原酶。
The minimal nitrogen cycle involves five reduction reactions and three oxidation reactions, each of which poses interesting problems in bioinorganic chemistry, energy transduction and protein structure/function relationships. Many of the major recent developments in this field have depended on the acquisition of protein crystal structures, including structures of enzymes with bound substrates or products and in protein-protein complexes. These enzymes include nitrogenase, nitrite reductases, hydroxylamine oxidoreductase and a fungal nitric oxide reductase.