The dose-dependent reduction in blood pressure through administration of magnesium. A double blind placebo controlled cross-over study.
The dose-dependent reduction in blood pressure through administration of magnesium. A double blind placebo controlled cross-over study.
复制标题
通过施用镁可实现剂量依赖性血压降低。
DOI：
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发表时间：
1993
影响因子：
3.2
通讯作者：
M. Wirell
中科院分区：
文献类型：
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作者：
L. Widman;P. Wester;B. Stegmayr;M. Wirell
从跑步健康筛查计划中招募17名舒张压超过90 mm Hg的患者，以参与镁补充的双盲交叉研究（15 mmol Mg 2 +/天（Emgesan，Kabi Pharmacia）持续3周，随后30 mmol Mg 2 +/天持续另外3周，最后以40 mmol Mg 2 +/天持续最后3周结束）。平均收缩压从154.0 +/- 10.7 mm Hg显著降低至146.1 +/- 16.9 mm Hg（P = 0.031），而平均舒张压从100.2 +/- 4.2 mm Hg降低至92.0 +/- 6.6 mm Hg（P = 0.0001）。
Seventeen patients with a diastolic blood pressure over 90 mm Hg were recruited from a running health screening program to participate in a double blind cross-over study of magnesium supplementation (15 mmol Mg2+/day (Emgesan, Kabi Pharmacia) for 3 weeks, followed by 30 mmol Mg2+/day for another 3 weeks, finishing with 40 mmol Mg2+/day for a final 3 weeks). A significant decrease in the mean systolic blood pressure was recorded from 154.0 +/- 10.7 mm Hg to 146.1 +/- 16.9 mm Hg (P = .031) while the mean diastolic blood pressure decreased from 100.2 +/- 4.2 mm Hg to 92.0 +/- 6.6 mm Hg (P = .0001).