Rabbit and monkey visual cortex:: more than a year of recording with up to 64 microelectrodes
Rabbit and monkey visual cortex:: more than a year of recording with up to 64 microelectrodes
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DOI：
10.1016/s0165-0270(99)00139-9
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发表时间：
2000-01-31
影响因子：
3
通讯作者：
Kr端ger, J
中科院分区：
文献类型：
--
作者：
Porada, I;Bondar, I;Kr端ger, J
在兔和绒猴的视皮层中，通过间接插入法分别长期植入32和64根微丝，以便从白色物质穿透皮层。在大多数电极上获得了超过1年的高质量动作电位记录。记录稳定性判断尖峰形状，尖峰列车自相关图，和尖峰率：在记录会话，稳定性基本上是完美的。几个电极的信号稳定的时期可以持续几天。提出了一种通过微X射线和随后的立体摄影测量来在体内重建电极位置的方法。动物福利方面被认为是。(C)2000 Elsevier Science B.V.保留所有权利。
In the visual cortex of rabbits and a marmoset monkey, 32 and 64 microwires, respectively, were chronically implanted by an indirect insertion method so that the cortex was penetrated from the white matter. For more than 1 year recordings of action potentials of good quality were obtained at most electrodes. Recording stability was judged by spike shape, spike train autocorrelograms, and spike rates: within recording sessions, stability was essentially perfect. Periods in which the signals of several electrodes were stable could last for several days. A method of in vivo reconstruction of the electrode locations by micro-X-rays and subsequent stereophotogrammetry is presented. The aspect of animal welfare is considered. (C) 2000 Elsevier Science B.V. All rights reserved.