The effect of comorbidity of restless legs syndrome and migraine
The effect of comorbidity of restless legs syndrome and migraine
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不宁腿综合征和偏头痛合并症的影响
DOI：
10.1007/s41105-015-0039-1
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
Koichi Hirata
中科院分区：
文献类型：
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作者：
Keisuke Suzuki. Masayuki Miyamoto;Tomoyuki Miyamoto;Shiho Suzuki;Yuichi Inoue;Momoyo Murata;Kentaro Matsui;Shingo Nishida;Kenichi Hayashida;Akira Usui;Yoichiro Ueki;Masaki Nakamura;Koichi Hirata
我们使用两种不同的临床环境（研究1，来自多中心研究的33名RLS患者;研究2，来自单中心研究的262名活动性偏头痛患者）评估了偏头痛和不宁腿综合征（RLS）合并症对睡眠和情绪的影响。虽然RLS患者中偏头痛的存在与睡眠问题或抑郁症状无关（研究1），但活动性偏头痛患者中RLS的存在与睡眠质量差，白天嗜睡和抑郁症状相关（研究2）。RLS是与活动性偏头痛相关的重要合并症;然而，临床环境尤其可能影响RLS与偏头痛的关联。
We evaluated the impact of migraine and restless legs syndrome (RLS) comorbidity on sleep and mood using two different clinical settings (Study 1, 33 RLS patients from a multicenter study; Study 2, 262 active migraine patients from a single-center study). Although the presence of migraine in RLS patients was not correlated with sleep problems or depressive symptoms (Study 1), the presence of RLS in active migraine patients was associated with poor sleep quality, daytime sleepiness and depressive symptoms (Study 2). RLS is an important comorbidity associated with active migraine; however, the clinical setting in particular may influence the RLS–migraine association.