Individual variability in functional connectivity predicts performance of a perceptual task
Individual variability in functional connectivity predicts performance of a perceptual task
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DOI：
10.1073/pnas.1113148109
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发表时间：
2012-02-28
影响因子：
11.1
通讯作者：
Corbetta, Maurizio
中科院分区：
文献类型：
--
作者：
Baldassarre, Antonello;Lewis, Christopher M.;Corbetta, Maurizio
人们执行新的知觉任务的能力不同，无论是在最初的接触过程中，还是在实践中的进步速度上。我们还知道，在学习过程中，被特定任务招募的大脑区域会改变它们的活动。在这里，我们研究神经信号预测个体在表现上的可变性。在一项新的视觉辨别任务的训练之前，我们使用静息状态功能磁共振来评估功能连通性。随后的任务表现与部分视觉皮质内以及视觉皮质和前额叶关联区之间的功能连通性测量有关。我们的结果表明，执行新颖知觉任务的个体差异可能与自发皮质活动的个体差异有关。
People differ in their ability to perform novel perceptual tasks, both during initial exposure and in the rate of improvement with practice. It is also known that regions of the brain recruited by particular tasks change their activity during learning. Here we investigate neural signals predictive of individual variability in performance. We used resting-state functional MRI to assess functional connectivity before training on a novel visual discrimination task. Subsequent task performance was related to functional connectivity measures within portions of visual cortex and between visual cortex and prefrontal association areas. Our results indicate that individual differences in performing novel perceptual tasks can be related to individual differences in spontaneous cortical activity.