Predicting membrane oxygenator pressure drop using computational fluid dynamics
Predicting membrane oxygenator pressure drop using computational fluid dynamics
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DOI：
10.1046/j.1525-1594.2002.07082.x
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发表时间：
2002-07-01
影响因子：
2.4
通讯作者：
Wagner, WR
中科院分区：
文献类型：
--
作者：
Gage, KL;Gartner, MJ;Wagner, WR
膜式氧合器的三维计算流体动力学（CFD）模拟应允许预测空间相关变量和随后的形状优化。纤维床的复杂性和当前的计算限制要求使用近似模型来预测完整设备模拟中的纤维阻力效应。对膜式氧合器进行了改良，以允许在所有主轴上沿着纤维束进行压力测量。实验压降与水灌注的信息被用来计算纤维束的渗透率。开发了商用膜式氧合器的三维CFD模型，以预测整个器械的压降。达西定律被用来解释纤维的粘性阻力，并作为动量损失项纳入守恒方程。在较低的流量下，实验和模拟的压力降之间显示出密切的协议，但在较高的流量下，模拟的压力降低于实验结果。纤维阻力效应和流场可视化的替代模型被建议作为潜在地提高流动模拟的准确性的手段。计算技术与实验验证相结合，提供了对模型有效性的深入了解，并显示出对膜式氧合器精确三维模拟的发展前景。
Three-dimensional computational fluid dynamic (CFD) simulations of membrane oxygenators should allow prediction of spatially dependent variables and subsequent shape optimization. Fiber bed complexity and current computational limitations require the use of approximate models to predict fiber drag effects in complete device simulations. A membrane oxygenator was modified to allow pressure measurement along the fiber bundle in all cardinal axes. Experimental pressure drop information with water perfusion was used to calculate the permeability of the fiber bundle. A three-dimensional CFD model of a commercial membrane oxygenator was developed to predict pressure drops throughout the device. Darcy's Law was used to account for the viscous drag of the fibers and was incorporated as a momentum loss term in the conservation equations. Close agreement was shown between experimental and simulated pressure drops at lower flow rates, but the simulated pressure drops were lower than experimental results at higher flows. Alternate models of fiber drag effects and flow field visualization are suggested as means to potentially improve the accuracy of the flow simulation. Computational techniques coupled with experimental verification offer insight into model validity and show promise for the development of accurate three-dimensional simulations of membrane oxygenators.