Acute carbohydrate ingestion does not influence the post-exercise iron-regulatory response in elite keto-adapted race walkers
Acute carbohydrate ingestion does not influence the post-exercise iron-regulatory response in elite keto-adapted race walkers
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DOI：
10.1016/j.jsams.2018.12.015
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发表时间：
2019-06-01
影响因子：
4
通讯作者：
Burke, Louise M.
中科院分区：
文献类型：
--
作者：
McKay, Alannah K. A.;Peeling, Peter;Burke, Louise M.
目的：坚持低碳水化合物（CHO）高脂肪（LCHF）饮食可以改变耐力运动员的铁代谢指标。本调查研究重新引入CHO之前，和在运动中的铁调节反应的运动在一个同质的（关于血清铁蛋白浓度）组的运动员适应LCHF diet.Design：平行组design.Methods：三个星期前的运动试验，23个精英竞走者坚持无论是CHO丰富（n = 14）或LCHF饮食（n = 9）。在运动员仍然坚持分配的饮食干预（Adapt）的情况下，进行标准化的19-25公里竞走。三天后进行了第二次测试，所有运动员都接受了高CHO饮食（CHO恢复）。分别于运动前、运动后及运动后3 h采集静脉血，测定血清白细胞介素6（IL-6）和铁调素25（hepcidin-25）水平（p < 0.001）在两种适应期间（LCHF：增加13.1倍; 95% CI：5.6-23.0，CHO：增加8.0倍; 5.1-11.1）和CHO恢复试验（LCHF：增加18.5倍; 10.9-28.9，CHO：增加6.3倍; 3.9-9.5）;试验间结局无差异（p = 0.84）。Hepcidin-25浓度在运动后3小时增加（p < 0.001），然而，它们在试验（p = 0.46）或饮食（p = 0.84）之间没有差异。结论：适应LCHF饮食的运动员中升高的IL-6反应并没有被外源CHO可用性的急性增加所减弱。尽管饮食诱导的IL-6对运动的反应存在差异，但饮食和试验之间的运动后铁调素水平相似，表明CHO可用性对运动后铁代谢的影响最小。(C)2019年澳大利亚运动医学由爱思唯尔有限公司出版。保留所有权利。
Objectives: Adhering to a low carbohydrate (CHO) high fat (LCHF) diet can alter markers of iron metabolism in endurance athletes. This investigation examined the re-introduction of CHO prior to, and during exercise on the iron-regulatory response to exercise in a homogenous (in regard to serum ferritin concentration) group of athletes adapted to a LCHF diet.Design: Parallel groups design.Methods: Three weeks prior to the exercise trials, twenty-three elite race walkers adhered to either a CHO-rich (n = 14) or LCHF diet (n = 9). A standardised 19-25 km race walk was performed while athletes were still adhering to their allocated dietary intervention (Adapt). A second test was performed three days later, where all athletes were placed on a high CHO diet (CHO Restoration). Venous blood samples were collected pre-, post- and 3 h post-exercise and measured for interleukin-6 (IL-6) and hepcidin-25.Results: The post-exercise IL-6 increase was greater in LCHF (p < 0.001) during both the Adapt (LCHF: 13.1-fold increase; 95% CI: 5.6-23.0, CHO: 8.0-fold increase; 5.1-11.1) and CHO Restoration trials (LCHF: 18.5-fold increase; 10.9-28.9, CHO: 6.3-fold increase; 3.9-9.5); outcomes were not different between trials (p = 0.84). Hepcidin-25 concentrations increased 3h post-exercise (p < 0.001), however, they did not differ between trials (p = 0.46) or diets (p = 0.84).Conclusions: The elevated IL-6 response in athletes adapted to a LCHF diet was not attenuated by an acute increase in exogenous CHO availability. Despite diet-induced differences in IL-6 response to exercise, post-exercise hepcidin levels were similar between diets and trials, indicating CHO availability has minimal influence on post-exercise iron metabolism. (C) 2019 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.