Distribution of apoA-I-containing HDL subpopulations in patients with coronary heart disease
Distribution of apoA-I-containing HDL subpopulations in patients with coronary heart disease
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DOI：
10.1161/01.atv.20.12.2670
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发表时间：
2000-12-01
影响因子：
8.7
通讯作者：
Schaefer, EJ
中科院分区：
文献类型：
--
作者：
Asztalos, BF;Roheim, PS;Schaefer, EJ
高密度脂蛋白(HDL)及其亚型在冠心病(CHD)的发生发展中起重要作用。用二维非变性凝胶电泳法测定了79例男性对照组和76例男性冠心病患者的高密度脂蛋白亚群，以检验载脂蛋白(Apo)A-I亚群在这两组人群中的差异是否大于传统的血脂水平。冠心病组高密度脂蛋白胆固醇(HDLc)较低(-14%，P
High density lipoproteins (HDLs) and their subspecies play a role in the development of coronary heart disease (CHD). HDL subpopulations were measured by 2-dimensional nondenaturing gel electrophoresis in 79 male control subjects and 76 male CHD patients to test the hypothesis that,greater differences in apolipoprotein (apo)A-I-containing HDL subpopulations would exist between these 2, groups than for traditional lipid levels. In CHD subjects, HDL cholesterol HDL-C) was lower (-14%, P