THE INFLUENCE OF DIFFERENT LIGHT SPECTRA ON THE SUPPRESSION OF PINEAL MELATONIN CONTENT IN THE SYRIAN-HAMSTER
THE INFLUENCE OF DIFFERENT LIGHT SPECTRA ON THE SUPPRESSION OF PINEAL MELATONIN CONTENT IN THE SYRIAN-HAMSTER
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DOI：
10.1016/0006-8993(84)91045-x
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发表时间：
1984-01-01
期刊：
影响因子：
2.9
通讯作者：
REITER, RJ
中科院分区：
文献类型：
--
作者：
BRAINARD, GC;RICHARDSON, BA;REITER, RJ
本研究的目的是测试不同可见光波长的光抑制仓鼠夜间松果体褪黑激素水平的能力。结果发现，可见光波长的干扰松果体褪黑激素的能力各不相同。在松果体褪黑激素产生的峰值期间，将动物暴露于半峰带宽为339-371 nm（近紫外线）、435-500 nm（蓝色）、510-550 nm（绿色）、558-636 nm（黄色）和653-668 nm（红色）的荧光光源。在每个实验中，将动物暴露于每个光源的相等辐照度。所用的不同辐照度为0.928、0.200、0.186、0.074和0.019 μW/cm 2。结果表明，蓝色荧光灯是最有效的抑制松果体褪黑激素。发现绿色荧光是抑制松果体褪黑激素的下一个最有效的光，其次是黄色荧光。近紫外线和红光是最不能够抑制松果体褪黑激素。这些观察结果表明，负责介导仓鼠松果体对光反应的视网膜色素可能是视紫红质或另一种蓝色敏感的发色团。
The purpose of this study was to test the capacity of different visible wavelengths of light to suppress nocturnal levels of pineal melatonin in hamsters. It was found that the visible wavelengths vary in their ability to perturb pineal melatonin. During the period of peak pineal melatonin production, animals were exposed to fluorescent light sources having half-peak bandwidths of 339–371 nm (near-ultraviolet), 435–500 nm (blue), 510–550 nm (green), 558–636 nm (yellow) and 653–668 nm (red). In each experiment, animals were exposed to equal irradiances of each light source. The different irradiances used were 0.928, 0.200, 0.186, 0.074 and 0.019 μW/cm2. The resultant data demonstrated that blue fluorescent light was the most efficient in suppressing pineal melatonin. Green fluorescent light was found to be the next most efficient light for inhibiting pineal melatonin followed by yellow fluorescent light. Near-ultraviolet and red light were the least capable of suppressing pineal melatonin. These observations suggest that the retinal photopigment responsible for mediating the pineal gland's response to light in the hamster may be either rhodopsin or another blue-sensitive chromophore.