Assessment of progression in knee osteoarthritis:: results of a 1 year study comparing arthroscopy and MRI
Assessment of progression in knee osteoarthritis:: results of a 1 year study comparing arthroscopy and MRI
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DOI：
10.1016/s1063-4584(03)00049-9
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发表时间：
2003-05-01
影响因子：
7
通讯作者：
Ayral, X
中科院分区：
文献类型：
--
作者：
Pessis, E;Drapé, JL;Ayral, X
目的：本研究的目的是确定胫骨股骨内侧室骨关节炎1年后对软骨病变磁共振成像（MRI）量化变化的敏感性，并评估软骨下骨髓水肿和骨异常对软骨病变进展的预测价值。设计：对20例有症状的膝关节内隔骨关节炎患者进行前瞻性、纵向研究。所有患者在入院当天和1年后分别通过负重x线片、三维梯度回波序列MRI、使用0.2 t专用MR设备和关节镜进行评估。采用MRI和法国关节镜学会（SFA）评分对内侧胫股软骨病变进行盲量化。首次MRI记录软骨下骨髓水肿和骨异常的存在，以评估其对1年后未变和恶化的软骨病变的影响。结果：1年后，x线平片和关节镜检查无统计学意义的变化。在方差上，使用SFA-MR评分的MRI发现软骨病变有统计学意义的恶化（P=0.01）。SFA-MR评分是最有效的结果。在最初的MR评估中没有软骨下骨异常和骨髓水肿预示着1年后没有恶化的软骨病变。结论：MRI在评估膝关节骨关节炎的进展方面表现出良好的前景。(C) 2003国际骨关节炎研究学会。Elsevier Science Ltd.出版。版权所有。
Objective: The objectives of this study were to determine the sensitivity to change of magnetic resonance imaging (MRI) quantification of chondropathy after 1 year in osteoarthritis of the medial tibiofemoral compartment and to assess the predictive value of subchondral bone marrow edema and bone abnormalities on progression of chondropathy.Design: Twenty patients with symptomatic knee osteoarthritis of the medial compartment underwent a prospective, longitudinal study. All patients were evaluated the same day at entry and after 1 year by plain weight-bearing radiographs, MRI with a three-dimensional gradient-echo sequence, using a 0.2-T dedicated MR unit, and arthroscopy. The medial tibiofemoral chondropathy was quantified blindly with MRI and arthroscopy using the French Society of Arthroscopy (SFA) score. Presence of subchondral bone marrow edema and bone abnormalities on initial MRI was recorded in order to evaluate their influence on both unchanged and worsened chondropathy after 1 year.Results: After 1 year, no statistically significant changes were observed with plain radiographs and arthroscopy. At variance, a statistically significant worsening of chondropathy was found with MRI using the SFA-MR score (P=0.01). SFA-MR score was the most responsive outcome. Absence of subchondral bone abnormalities and bone marrow edema on initial MR assessment predicted absence of worsening of chondropathy after 1 year.Conclusion: MRI appears promising for evaluating progression of knee osteoarthritis. (C) 2003 OsteoArthritis Research Society International. Published by Elsevier Science Ltd. All rights reserved.