KESHAN DISEASE - AN ENDEMIC CARDIOMYOPATHY IN CHINA
KESHAN DISEASE - AN ENDEMIC CARDIOMYOPATHY IN CHINA
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DOI：
10.1016/s0046-8177(85)80110-6
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发表时间：
1985-01-01
期刊：
影响因子：
3.3
通讯作者：
LI, C
中科院分区：
文献类型：
--
作者：
LI, G;WANG, F;LI, C
克山病是我国的一种地方性心肌病。在形态学上，该病症的特征在于心肌的多灶性坏死和替代性纤维化，导致急性或慢性心力衰竭。部分克山病患者具有充血性（扩张性）心肌病的临床特征，但两者的病理特征不同。克山病的病因尚不清楚。许多因素可能协同作用导致疾病。
Keshan disease is an endemic cardiomyopathy in China. Morphologically, the condition is characterized by multifocal necrosis and replacement fibrosis of the myocardium, resulting in acute or chronic heart failure. Some patients with Keshan disease show the clinical features of congestive (dilated) cardiomyopathy, but the pathologic features of the 2 conditions are different. The etiology of Keshan disease remains unknown. Numerous agents probably work synergistically to cause the disease.