A general practitioner's guide to hematopoietic stem-cell transplantation
A general practitioner's guide to hematopoietic stem-cell transplantation
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DOI：
10.3747/co.26.5033
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发表时间：
2019-06-01
期刊：
影响因子：
2.6
通讯作者：
Popradi, G.
中科院分区：
文献类型：
--
作者：
Bazinet, A.;Popradi, G.
造血干细胞移植（HSCT）是一种医疗程序，包括在短期化疗或放疗后注入干细胞，或两者兼而有之。它可以用于治疗各种癌症，以及一些良性疾病。在本综述中，我们讨论了各种类型的HSCT及其主要适应症。移植程序本身的原则和受体选择的基础进行审查。特别关注HSCT的近期和远期并发症及其处理策略。造血干细胞移植是一种潜在的挽救生命的方法，通常是治疗各种疾病的唯一选择;然而，它并非没有明显的毒性。
Hematopoietic stem-cell transplantation (HSCT) is a medical procedure that consists of infusing stem cells after a short course of chemotherapy or radiotherapy, or both. It can be used in the treatment of various cancers, as well as some benign conditions. In the present review, we discuss the various types of HSCT and their main indications. The principles of the transplant procedure itself and the basics of recipient selection are reviewed. Special attention is given to both the i m nee d late and the long-term complications of HSCT and t heir management strategies. Hematopoietic stem-cell transplantation is a potentially life-saving procedure and often the only curative option for a variety of diseases; however, it is not without significant toxicities.