From circuits to behaviour in the amygdala.

From circuits to behaviour in the amygdala.
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从杏仁核中的电路到行为。

DOI:
10.1038/nature14188
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发表时间:
2015-01-15
期刊:
影响因子:
64.8
通讯作者:
Tye KM
Tye KM
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Janak PH;Tye KM

文献摘要

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杏仁核长期以来一直与情绪和动机有关,在处理恐惧和奖励环境刺激方面发挥着重要作用。一个单一的结构怎么可能对如此不同的功能至关重要?随着最近的技术进步,可以对特定神经回路元件进行因果调查,我们现在可以开始将杏仁核的复杂解剖连接映射到行为功能上。要了解杏仁核是如何影响一系列行为的,就需要研究不同的杏仁核回路。
The amygdala has long been associated with emotion and motivation, playing an essential part in processing both fearful and rewarding environmental stimuli. How can a single structure be crucial for such different functions? With recent technological advances that allow for causal investigations of specific neural circuit elements, we can now begin to map the complex anatomical connections of the amygdala onto behavioural function. Understanding how the amygdala contributes to a wide array of behaviours requires the study of distinct amygdala circuits.