ANTI-N-METHYL D-ASPARTATE RECEPTOR ENCEPHALITIS MIMICS VIRAL ENCEPHALITIS

ANTI-N-METHYL D-ASPARTATE RECEPTOR ENCEPHALITIS MIMICS VIRAL ENCEPHALITIS
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DOI:
10.1097/inf.0b013e31823d52eb
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发表时间:
2012-02-01
影响因子:
3.6
通讯作者:
Roy-Burman, Arup
Roy-Burman, Arup
中科院分区:
医学4区
文献类型:
--
作者:
Bseikri, Mustafa R.;Barton, Jubilee R.;Roy-Burman, Arup

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我们描述了3例儿童精神舞蹈样脑炎与抗N-甲基D-天冬氨酸受体自身抗体的临床过程。这些病例,包括迄今为止最严重的医学复杂的幸存者,说明了诊断,支持性护理和免疫调节治疗的挑战。临床和实验室特征与病毒性脑炎相似,通过适当的诊断和治疗,病情往往是可逆的。
We describe the clinical courses of 3 children with a psychochoreiform encephalitis associated with anti-N-methyl D-aspartate receptor autoantibodies. These cases, including the most severely medically complicated survivor to date, illustrate the challenges of diagnosis, supportive care, and immune-modulating therapy. Clinical and laboratory features are similar to those of viral encephalitis, and the condition is often reversible with appropriate diagnosis and treatment.