Evaluation of effects of perioperative oral care intervention on hospitalization stay and postoperative infection in patients undergoing lung cancer intervention
Evaluation of effects of perioperative oral care intervention on hospitalization stay and postoperative infection in patients undergoing lung cancer intervention
复制标题
围手术期口腔护理干预对肺癌介入患者住院天数及术后感染的影响
DOI：
10.1007/s00520-020-05450-9
复制
发表时间：
2020-04-22
影响因子：
3.1
通讯作者：
Iino, Mitsuyoshi
中科院分区：
文献类型：
--
作者：
Ishikawa, Shigeo;Yamamori, Iku;Iino, Mitsuyoshi
目的 本回顾性研究探讨围术期口腔护理干预对肺癌切除患者术后住院时间和术后呼吸道感染发生率的影响。方法 585例因肺癌接受肺切除术的患者，397例接受围手术期口腔护理干预，其余188例未接受。本研究回顾性调查了各组的人口统计学和临床特征（包括术后并发症和术后住院时间）。为了确定围手术期口腔护理干预是否与术后住院时间或术后呼吸道感染独立相关，我们进行了多变量分析、多元回归分析和多变量逻辑回归分析。结果 与肺癌手术患者术后住院时间延长显着相关的参数是年龄较大、术后并发症、术中出血增加、侵入性更大的手术方法（例如开放手术）以及缺乏围手术期口腔护理干预（标准偏回归系数（ss）= 0.083，p = 0.027）。此外，年龄较大、手术时间较长是术后呼吸道感染发生的显着独立危险因素。缺乏围手术期口腔护理干预是发生术后呼吸道感染的潜在危险因素，尽管没有统计学意义（比值比 = 2.448，95% 置信区间 = 0.966-6.204，p = 0.059）。结论 这些结果凸显了肺癌手术前围手术期口腔护理干预的重要性，以缩短术后住院时间并降低术后呼吸道感染的风险。
Purpose This retrospective study investigated the effect of perioperative oral care intervention on postoperative outcomes in patients undergoing lung cancer resection, in terms of the length of postoperative hospital stay and the incidence of postoperative respiratory infections. Methods In total, 585 patients underwent lung resection for lung cancer, 397 received perioperative oral care intervention, whereas the remaining 188 did not. This study retrospectively investigated the demographic and clinical characteristics (including postoperative complications and postoperative hospital stay) of each group. To determine whether perioperative oral care intervention was independently associated with either postoperative hospital stay or postoperative respiratory infections, multivariate analysis, multiple regression analysis, and multivariate logistic regression analysis were conducted. Results Parameters significantly associated with a prolonged postoperative hospital stay in lung cancer surgery patients were older age, postoperative complications, increased intraoperative bleeding, more invasive operative approach (e.g., open surgery), and lack of perioperative oral care intervention (standard partial regression coefficient (ss) = 0.083, p = 0.027). Furthermore, older age and longer operative time were significant independent risk factors for the occurrence of postoperative respiratory infections. Lack of perioperative oral care intervention was a potential risk factor for the occurrence of postoperative respiratory infections, although not statistically significant (odds ratio = 2.448, 95% confidence interval = 0.966-6.204, p = 0.059). Conclusion These results highlight the importance of perioperative oral care intervention prior to lung cancer surgery, in order to shorten postoperative hospital stay and reduce the risk of postoperative respiratory infections.