Color doppler imaging of ocular hemodynamic changes in Behcet's disease
Color doppler imaging of ocular hemodynamic changes in Behcet's disease
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DOI：
10.1007/s10384-003-0024-0
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发表时间：
2004-03-01
影响因子：
2.4
通讯作者：
Sakalar, YB
中科院分区：
文献类型：
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作者：
Çaça, I;Nazaroglu, H;Sakalar, YB
目的：白塞病患者的眼血流速度进行了前瞻性评估，以确定其changes.Methods：受试者被分为三组：白塞病的眼睛参与（goup I），白塞病的眼睛没有参与（goup II），和对照组（组III）。第I组27只眼，第II组和第III组各28只眼。采用彩色多普勒超声（CDU）检测视网膜中央动脉（CRA）、眼动脉（OA）、鼻睫状后动脉（NPCA）和颞睫状后动脉（TPCA）的血流，测定收缩期峰值血流速度（PSV）、舒张末期血流速度（EDV）和阻力指数（RI）。测量视网膜中央静脉（CRV）的平均血流速度。结果：Ⅰ、Ⅱ组CRA PSV值均显著低于对照组（P < 0.001，P = 0.018）;Ⅰ组CRA的PSV值明显低于Ⅱ组（P < 0.001）。I组和II组CRA的EDV值均显著低于对照组（P < 0.001，P = 0.034）。I组CRA的EDV值显著低于II组（P = 0.041），I组OA的PSV值显著低于对照组（P = 0.002）。I组OA的EDV值显著低于II组和对照组（P = 0.001和P = 0.037）。I组NPCA的PSV值显著低于对照组（P = 0.007）。TPCA的PSV值I、II组均显著低于对照组（P < 0.001）。P < 0.001。分别）。I组TPCA的EDV值显著低于II组和对照组（分别为P = 0.014和P = 0.003）。结论：白塞病患者的眶动脉血流明显减少，且以眼部受累者更为明显。这可能是闭塞性血管炎的结果，这是常见于白塞病患者的视网膜血管。(C)日本眼科学会2004年。
Purpose: A prospective evaluation of the Ocular blood flow velocity in patients with Behcet's disease was carried out to determine its changes.Methods: Subjects were divided into three groups: those with ocular involvement in Behcet's disease (goup I), those without ocular involvement in Behcet's disease (goup II), and a control group (group III). Twenty-seven eyes in group I and 28 eyes each in groups II and III were investigated. The blood flow in the central retinal artery (CRA), ophthalmic artery (OA), nasal posterior ciliary artery (NPCA), and the temporal posterior ciliary artery (TPCA) was measured using color Doppler ultrasonography (CDU) to determine the peak systolic velocity (PSV), end diastolic velocity (EDV), and resistivity index (RI). The mean blood flow velocity of the central retinal vein (CRV) was also measured. These results were then compared among the three groups of subjects.Results: The PSV values of CRA in groups I and II were found to he significantly lower than those in the control group (P < 0.001, P = 0.018, respectively). The PSV values of CRA in group I were found to be significantly lower than those in group II (P < 0.001). The EDV values of CRA in groups I and II were found to be significantly lower than those in the control group (P < 0.001, P = 0.034, respectively). The EDV values of CRA in group I were significantly lower than those in group II (P = 0.041).The PSV values of OA in group I were significantly lower than those in the control group (P = 0.002). The EDV values of OA in group I were significantly lower than those values in group II or the control group (P = 0.001 and P = 0.037. respectively).The PSV values of NPCA in group I were significantly lower than those ill the control group (P = 0.007). The PSV Values of TPCA in groups I and II were significantly lower than those ill the control group (P < 0.001. P < 0.001. respectively). The EDV values of TPCA in group I were significantly lower than those values in group II or the control group (P = 0.014 and P = 0.003, respectively). There were no significant differences in the mean blood flow values of the CRV among all three groups (P > 0.05).Conclusions: There are significant reductions in the blood flow values of the orbital arteries in patients with Behcet's disease, and they are more evident in those with ocular involvement. This might be the result of occlusive vasculitis, which is frequently seen in the retinal vessels of patients with Behcet's disease. (C) Japanese Ophthalmological Society 2004.