Clinical orofacial characteristics associated with risk of first-onset TMD: the OPPERA prospective cohort study.
Clinical orofacial characteristics associated with risk of first-onset TMD: the OPPERA prospective cohort study.
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与第一届TMD风险相关的临床口面特征：Oppera前瞻性队列研究。
DOI：
10.1016/j.jpain.2013.07.018
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发表时间：
2013-12
期刊：
影响因子：
4
通讯作者：
Slade, Gary D.
中科院分区：
文献类型：
--
作者：
Ohrbach, Richard;Bair, Eric;Fillingim, Roger B.;Gonzalez, Yoly;Gordon, Sharon M.;Lim, Pei-Feng;Ribeiro-Dasilva, Margarete;Diatchenko, Luda;Dubner, Ronald;Greenspan, Joel D.;Knott, Charles;Maixner, William;Smith, Shad B.;Slade, Gary D.
病例对照研究已经记录了慢性颞下颌关节紊乱病（TMD）的临床表现，而TMD发展的临床预测因素在很大程度上是未知的。我们在一项针对18-44岁美国成年人的前瞻性队列研究中评估了41项被认为可预测首发TMD的临床口面特征。在中位2.8年的随访期间，2，737人完成了季度筛选问卷。对报告症状的人进行了检查，发现260人患有首发TMD。单变量和多变量考克斯回归模型量化了基线临床口面指标与TMD发病率之间的相关性。基线自我报告工具的重要预测因素包括口腔功能异常、既往面部疼痛及其对生活的影响、TMJ噪音和颌锁定以及非特异性口面症状。基线临床检查的重要预测因素是下颌张开时疼痛和咀嚼肌、颈部和身体肌肉触诊疼痛。颞下颌关节噪音和牙齿磨损方面的检查评估没有预测发病率。在多变量分析中，非特异性口面症状，疼痛从下颌打开和口腔功能异常预测TMD的发病率。结果表明，只有少数口面部检查结果影响TMD的发病率，只有在适度的程度。自我报告的症状，特别是那些似乎反映了咀嚼组织以外的系统的变化，发现更明显的影响。
Case-control studies have documented clinical manifestations of chronic temporomandibular disorders (TMD), whereas clinical predictors of TMD development are largely unknown. We evaluated 41 clinical orofacial characteristics thought to predict first-onset TMD in a prospective cohort study of U.S. adults aged 18-44 years. During the median 2.8-year follow-up period, 2,737 people completed quarterly screening questionnaires. Those reporting symptoms were examined and 260 people were identified with first-onset TMD. Univariate and multivariate Cox regression models quantified associations between baseline clinical orofacial measures and TMD incidence. Significant predictors from baseline self-report instruments included oral parafunctions, prior facial pain and its life-impact, TMJ noises and jaw locking, and non-specific orofacial symptoms. Significant predictors from the baseline clinical examination were pain on jaw opening and pain from palpation of masticatory, neck, and body muscles. Examiner assessments of TMJ noise and tooth wear facets did not predict incidence. In multivariate analysis, non-specific orofacial symptoms, pain from jaw opening and oral parafunctions predicted TMD incidence. The results indicate that only a few orofacial examination findings influenced TMD incidence, and only to a modest degree. More pronounced influences were found for self-reported symptoms, particularly those that appeared to reflect alterations to systems beyond the masticatory tissues.
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影响因子：
4
作者：
Bair, Eric;Ohrbach, Richard;Slade, Gary D.
通讯作者：
Slade, Gary D.
影响因子：
2.9
作者：
Gavish, A;Halachmi, M;Gazit, E
通讯作者：
Gazit, E
影响因子：
4
作者：
Bair, Eric;Brownstein, Naomi C.;Slade, Gary D.
通讯作者：
Slade, Gary D.
DOI：
10.1016/j.jpain.2011.08.002
发表时间：
2011-11
期刊：
The journal of pain
影响因子：
--
作者：
Maixner W;Diatchenko L;Dubner R;Fillingim RB;Greenspan JD;Knott C;Ohrbach R;Weir B;Slade GD
通讯作者：
Slade GD
影响因子：
7.6
作者：
Huang, GJ;LeResche, L;Drangsholt, MT
通讯作者：
Drangsholt, MT