Phrenic motoneurons receive monosynaptic inputs from the Kölliker–Fuse nucleus: a light- and electron-microscopic study in the rat
Phrenic motoneurons receive monosynaptic inputs from the Kölliker–Fuse nucleus: a light- and electron-microscopic study in the rat
复制标题
膈运动神经元接收来自 Kölliker-Fuse 核的单突触输入：大鼠的光镜和电子显微镜研究
DOI：
10.1016/s0006-8993(00)03106-1
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发表时间：
2001
期刊：
影响因子：
2.9
通讯作者：
Y. Yasui
中科院分区：
文献类型：
--
作者：
S. Yokota;T. Tsumori;K. Ono;Y. Yasui
臂旁复合体在呼吸调节中起重要作用，已有报道将投射纤维投射至膈核，但臂旁纤维与膈运动神经元之间的突触组织尚未见报道。用顺行和逆行追踪的方法，在大鼠臂旁纤维中发现，主要起源于Kölliker-Fuse核(KF)的纤维不仅终止于膈核内，而且终止于膈运动神经元的放射状树突束。结果表明，KF纤维主要与隔核运动神经元的树突形成非对称性突触，部分与胞体形成突触。这些数据表明，KF的输出信号可能直接对膈运动神经元产生兴奋性影响。
The parabrachial complex, which plays an important role in respiratory regulation, has been reported to send projection fibers to the phrenic nucleus, but the synaptic organization between the parabrachial fibers and the phrenic motoneurons has not been examined. Using anterograde and retrograde tracing methods, we found in the rat that the parabrachial fibers originating mainly from the Kölliker–Fuse nucleus (KF) terminated not only within the phrenic nucleus but also on the radial dendritic bundles of the phrenic motoneurons. It was further revealed that the KF fibers made asymmetrical synapses predominantly with dendrites and partly with somata of the phrenic motoneurons. These data suggest that output signals from the KF may exert excitatory influence directly upon the phrenic motoneurons.