Highly functionalized pyranopyrans from furans: A synthesis of the C27-C38 and C44-C53 subunits of norhalichondrin B

Highly functionalized pyranopyrans from furans: A synthesis of the C27-C38 and C44-C53 subunits of norhalichondrin B
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DOI:
10.1021/ol702559e
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发表时间:
2007-12-06
期刊:
影响因子:
5.2
通讯作者:
Phillips, Andrew J.
Phillips, Andrew J.
中科院分区:
化学1区
文献类型:
--
作者:
Henderson, James A.;Jackson, Katrina L.;Phillips, Andrew J.

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在针对norhalichondrin B的研究的背景下,描述了基于Achmatowicz氧化然后是显著非对映选择性Kishi还原的高度官能化的吡喃吡喃的合成。
A synthesis of highly functionalized pyranopyrans based on an Achmatowicz oxidation followed by a remarkably diastereoselective Kishi reduction is described in the context of studies directed toward norhalichondrin B.