Differential expression of secretion machinery during bacterial growth: SecY and SecF decrease while SecA increases during transition from exponential phase to stationary phase.
Differential expression of secretion machinery during bacterial growth: SecY and SecF decrease while SecA increases during transition from exponential phase to stationary phase.
复制标题
细菌生长过程中分泌机制的差异表达：从指数期到稳定期的过渡期间，SecY 和 SecF 减少，而 SecA 增加。
DOI：
10.1007/s00284-013-0421-7
复制
发表时间：
2013
影响因子：
2.6
通讯作者：
Tai,PhangC
中科院分区：
文献类型：
--
作者：
Yang,Chun-Kai;Lu,Chung-Dar;Tai,PhangC
Transcription of many house-keeping genes, includingsecYand some othersecgenes, decreases in the transition from the exponential phase to the stationary phase (feast to famine) inBacillus subtilis. Unexpectedly and in contradiction to earlier reports, enhanced transcription was observed for another group ofsecgenes, includingsecAwhich codes for an essential ATPase for protein secretion. Consistent with the transcription data, the SecA protein ofB. subtilisincreases significantly in the stationary phase. Immunoblot analyses of Sec proteins during the transition inEscherichia colialso revealed the pronounced decreases of SecY and SecF and the increase of SecA, resulting in drastic increases of SecA/SecY and SecA/SecF ratios from exponential to stationary phases. The differential expression of Sec proteins in the stationary phase suggests the possibility of specific physiological functions.
