Serotonin syndrome after concomitant treatment with linezolid and meperidine
Serotonin syndrome after concomitant treatment with linezolid and meperidine
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DOI：
10.1086/524671
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发表时间：
2008-01-15
影响因子：
11.8
通讯作者：
Forrest, Donna L.
中科院分区：
文献类型：
--
作者：
Das, Prabodh K.;Warkentin, Dawn I.;Forrest, Donna L.
已报告利奈唑胺和5-羟色胺再摄取抑制剂给药后出现5-羟色胺综合征。哌替啶阻断神经元对5-羟色胺的再摄取。尚未描述利奈唑胺和哌替啶联合治疗后的血清素综合征。我们描述了一名27岁的急性白血病男性患者在同时使用利奈唑胺和哌替啶后出现的5-羟色胺综合征。
Serotonin syndrome has been reported with administration of linezolid and serotonin reuptake inhibitors. Meperidine blocks the neuronal reuptake of serotonin. Serotonin syndrome after concomitant linezolid and meperidine therapy has not been described. We describe serotonin syndrome after concomitant use of linezolid and meperidine in a 27-year-old man with acute leukemia.