Plasma cortisol secretion and REM period latency in adult endogenous depression.
Plasma cortisol secretion and REM period latency in adult endogenous depression.
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成人内源性抑郁症的血浆皮质醇分泌和快速眼动期潜伏期。
DOI：
10.1176/ajp.140.6.750
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Puig-Antich,J
中科院分区：
文献类型：
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作者：
Asnis,GM;Halbreich,U;Sachar,EJ;Nathan,RS;Ostrow,LC;Novacenko,H;Davis,M;Endicott,J;Puig-Antich,J
本文研究了25例内源性抑郁症患者血浆皮质醇分泌与REM潜伏期的关系。与皮质醇分泌正常的17例患者相比，皮质醇分泌过多的8例患者（32%）的REM期潜伏期显着缩短。此外，极短的REM潜伏期（20分钟或更短）几乎只发生在皮质醇分泌过多的患者中。作者讨论了可能的神经递质紊乱负责这些异常和这些发现的临床意义。
The authors studied the relationship of plasma cortisol secretion and REM period latency in 25 patients with endogenous depression. The 8 patients (32%) with cortisol hypersecretion had a significantly shortened REM period latency in comparison with the 17 with normal cortisol secretion. Furthermore, an extremely short REM latency (20 minutes or less) occurred almost exclusively in those with cortisol hypersecretion. The authors discuss possible neurotransmitter disturbances responsible for these abnormalities and the clinical implications of these findings.