Antioxidant activity of the ethanolic extract of Striga orobanchioides
Antioxidant activity of the ethanolic extract of Striga orobanchioides
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DOI：
10.1016/s0378-8741(03)00021-7
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发表时间：
2003-04-01
影响因子：
5.4
通讯作者：
Suresh, B
中科院分区：
文献类型：
--
作者：
Badami, S;Gupta, MK;Suresh, B
据报道，含有黄酮类化合物的植物具有很强的抗氧化特性。使用标准程序筛选独脚金的乙醇提取物的体外和体内抗氧化特性。在DPPH和一氧化氮自由基抑制试验中，乙醇提取物的IC 50值分别为18.65 +/- 1.46和11.20 +/- 0.52 μ g/ml。这些值小于作为标准品的抗坏血酸和芦丁所得值。在体内实验中，100 mg/kg体重剂量的浸提液处理导致肝脏和肾脏中过氧化氢酶水平显著增加。观察到肝脏中SOD水平显著增加。处理还引起TBA-RS的显著降低和抗坏血酸水平的增加。这些结果表明，S乙醇提取物具有较强的抗氧化潜力。竹节虫(C)2003爱思唯尔科学爱尔兰有限公司保留所有权利。
Plants containing flavonoids have been reported to possess strong antioxidant properties. The ethanolic extract of Striga orobanchioides was screened for in vitro and in vivo antioxidant properties using standard procedures. The ethanol extract exhibited IC50 values of 18.65 +/- 1.46 and 11.20 +/- 0.52 mug/ml, respectively in DPPH and nitric oxide radical inhibition assays. These values were less than those obtained for ascorbic acid and rutin, used as standards. In the in vivo experiments the extract treatment at 100 mg/kg body weight dose caused a significant increase in the level of the catalase in the liver and the kidneys. A significant increase in the level of SOD in the liver was observed. The treatment also caused a significant decrease in the TBA-RS and increase in the ascorbic acid levels. These results suggest strong antioxidant potentials of the ethanolic extract of S. orobanchioides. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.