EFFECTS OF INSULIN ON ADAPTATION OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE AND 6-PHOSPHOGLUCONATE DEHYDROGENASE IN RAT ADIPOSE-TISSUE
EFFECTS OF INSULIN ON ADAPTATION OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE AND 6-PHOSPHOGLUCONATE DEHYDROGENASE IN RAT ADIPOSE-TISSUE
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DOI：
10.1016/0304-4165(72)90248-6
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发表时间：
1972-01-01
期刊：
影响因子：
--
通讯作者：
HANSEN, RJ
中科院分区：
文献类型：
--
作者：
GEISLER, RW;HANSEN, RJ
1.1.研究胰岛素对脂肪组织葡萄糖-6-磷酸脱氢酶和6-磷酸葡萄糖酸脱氢酶的影响.在生理浓度的葡萄糖，胰岛素，加入到孵育培养基中，刺激活性的葡萄糖-6-磷酸脱氢酶，但不是6-磷酸葡萄糖酸脱氢酶，在附睾脂肪组织，从饥饿或糖尿病大鼠，incubatedin vitrofor 16小时。抑制剂放线菌素D（5 μg/ml）和放线菌酮（1 mg/ml）可阻断胰岛素刺激。
1.1. The effects of insulin on adipose tissue glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase were studied.2.2. At physiological concentrations of glucose, insulin, added to the incubation medium, stimulated the activity of glucose-6-phosphate dehydrogenase, but not 6-phosphogluconate dehydrogenase, in epididymal adipose tissue, from starved or diabetic rats, incubatedin vitrofor 16 h.3.3. The inhibitors actinomycin D (5 μg/ml) and cycloheximide (1 mg/ml) blocked the insulin stimulation.