The spatial organization of the genome in mammalian cells.
The spatial organization of the genome in mammalian cells.
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DOI：
10.1016/j.gde.2004.02.008
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发表时间：
2004-04
影响因子：
4
通讯作者：
T. Pederson
中科院分区：
文献类型：
--
作者：
T. Pederson
A number of recent studies have indicated that the location of a given mammalian chromosome within the interphase nucleus is related to its size, whereas other work has implicated a chromosome’s gene density as a factor. Recent investigations of the degree to which an ordered arrangement of mitotic chromosomes on the metaphase plate is inherited and perpetuated during successive cell cycles have also yielded somewhat controversial results. The arrangement of chromosomes in the nucleus also has been investigated by the analysis of chromosomal translocations, with some surprising recent findings.
