Dietary and plasma lipid, lipoprotein, and apolipoprotein profiles among elderly Hispanics and non-Hispanics and their association with diabetes
Dietary and plasma lipid, lipoprotein, and apolipoprotein profiles among elderly Hispanics and non-Hispanics and their association with diabetes
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DOI：
10.1093/ajcn/76.6.1214
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发表时间：
2002-12-01
影响因子：
7.1
通讯作者：
Tucker, KL
中科院分区：
文献类型：
--
作者：
Bermudez, OI;Velez-Carrasco, W;Tucker, KL
背景：关于美国西班牙裔老年人饮食摄入量和血脂的数据有限。目的：人群中2型糖尿病患病率的差异强调了我们评估心血管疾病的饮食和血浆危险因素的必要性。设计：测量老年受试者（60-98岁）的血浆脂质、载脂蛋白和大量营养素的膳食摄入量：490名加勒比裔西班牙人（波多黎各人和多米尼加人）和163名非西班牙裔白人。血浆值与种族和大量营养素摄入有关。对西班牙裔糖尿病患者血浆脂质的差异进行了评估。结果：西班牙裔白人的碳水化合物和多不饱和脂肪酸的摄入量高于非西班牙裔白人，胆固醇、饱和脂肪酸和单饱和脂肪酸的摄入量低于非西班牙裔白人。西班牙裔女性的总胆固醇、高密度脂蛋白胆固醇和载脂蛋白a - 1浓度显著低于非西班牙裔白人女性；男性也出现了类似的趋势。血脂异常（高甘油三酯和低高密度脂蛋白胆固醇）在西班牙裔糖尿病患者中比非糖尿病患者更为普遍。结论：血脂存在种族差异，并且似乎与饮食摄入量的差异有关。然而，西班牙裔和非西班牙裔白人的脂质谱都表明心血管疾病的高风险。西班牙裔糖尿病患者患血脂异常的风险高于非糖尿病患者。我们的数据表明，生活方式的改变，包括饮食调整和锻炼，可能对两个民族都有显著的好处。
Background: There are limited data about dietary intakes and plasma lipids of elderly US Hispanics.Objective: The disparity in prevalence of type 2 diabetes among population groups underscored our need to assess dietary and plasma risk factors for cardiovascular disease.Design: Plasma lipids and apolipoproteins and dietary intakes of macronutrients were measured in elderly subjects (60-98 y): 490 Hispanics of Caribbean origin (Puerto Ricans and Dominicans) and 163 non-Hispanic whites. Plasma values were related to ethnicity and to macronutrient intake. Differences in plasma lipids due to diabetes were assessed among the Hispanics.Results: Intakes of carbohydrate and polyunsaturated fatty acids were higher and intakes of cholesterol and saturated and monoun-saturated fatty acids were lower in Hispanics than in non-Hispanic whites.Concentrations of total cholesterol, HDL cholesterol, and apolipoprotein A-I were significantly lower among Hispanic women than among non-Hispanic white women; a similar trend was seen in men. Dyslipidemia (high triacylglycerols and low HDL cholesterol) was more prevalent among Hispanics with than without diabetes. Conclusions: Ethnic differences in serum lipids exist and appear to be associated with differences in dietary intakes. However, both Hispanics and non-Hispanic whites had lipid profiles indicating a high risk of cardiovascular disease. Hispanics with diabetes were at higher risk of dyslipidemia than were those without diabetes. Our data suggest that lifestyle changes, including diet modification and exercise, could be of significant benefit to both ethnic groups.