Mood variability in anxiety disorders
Mood variability in anxiety disorders
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DOI：
10.1016/j.jad.2005.12.050
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发表时间：
2006-04-01
影响因子：
6.6
通讯作者：
Bowen, A
中科院分区：
文献类型：
--
作者：
Bowen, R;Baetz, M;Bowen, A
背景：探讨焦虑障碍患者是否比对照组有更多的情绪变化。方法：采用状态-特质焦虑量表（STAIT）、贝克抑郁量表（BDI）、心境障碍问卷（MDQ）和tempa气质问卷对28例焦虑障碍患者和28例对照组进行评估。连续7天，参与者使用视觉模拟量表（VAS）对早上和晚上的低、高和焦虑情绪进行评分。使用均方连续差（MSSD）和平均标准误差（SEM）计算情绪变异性，两者均来自VAS评分。结果：(1)患者低情绪和焦虑变异性的MSSD和SEM测量高于对照组。患者的高情绪扫描电镜略高。(2)高情绪量表分为两组：(a) VAS高情绪量表和TEMPS高情绪量表的平均值明显测量适应性高情绪或高情绪，与抑郁（BDI）不相关或负相关。(b) VAS高情绪量表的MSSD、TEMPS生理节律紊乱量表、MDQ三者之间存在相关性，且与BDI呈可变高情绪、苦恼性相关。局限性：样本量小。结论：焦虑障碍患者比对照组表现出更多的情绪变异性。我们还发现了适应性高情绪和可变高情绪的测量差异，后者与抑郁有关。情绪变异性是焦虑障碍患者痛苦的一个重要但被忽视的方面。(c) 2006 Elsevier B.V.版权所有
Background: To investigate whether patients with anxiety disorders have more variable mood than control subjects.Methods: Twenty-eight patients with anxiety disorders and 28 controls were assessed with the State-Trait Anxiety Inventory-Trait form (STAIT), Beck Depression Inventory (BDI), Mood Disorder Questionnaire (MDQ), and TEMPS-A questionnaire for temperament. Participants used Visual Analogue Scales (VAS) to rate low, high and anxious moods, morning and evening, for 7 consecutive days. Mood variability was calculated with the Mean Square Successive Difference (MSSD) and the Standard Error of the Mean (SEM), both derived from the VAS ratings.Results: (1) The MSSD and SEM measures for low mood and anxiety variability were higher in patients than controls. The SEM for high mood was marginally higher in patients. (2) The high mood measures separated into two clusters: (a) the mean of the VAS high mood scale and the TEMPS hyperthymia scale apparently measure an adaptive high mood or hyperthymia that did not correlate or correlated negatively with depression (BDI). (b) The MSSD of the VAS high mood scale, the TEMPS cyclothymia scale, and the MDQ correlated with each other and with the BDI as variable high mood that is distressing.Limitations: Small sample size.Conclusions: Patients with anxiety disorders show more mood variability than controls. We also found a difference in the measures of adaptive high mood from variable high mood, the latter associated with depression. Mood variability is an important but neglected aspect of distress in patients with anxiety disorders. (c) 2006 Elsevier B.V. All rights reserved.