Current status of brachytherapy in cancer treatment - short overview.
Current status of brachytherapy in cancer treatment - short overview.
复制标题
DOI：
10.5114/jcb.2017.72607
复制
发表时间：
2017-12
影响因子：
1.4
通讯作者：
Skowronek J
中科院分区：
文献类型：
--
作者：
Skowronek J
癌症发病率和死亡率取决于许多因素，包括年龄、社会经济地位和地理位置，其发病率在世界各地不断上升。大多数癌症治疗包括外部放射治疗或近距离治疗。近距离放射疗法是一种将放射性核素的能量直接插入肿瘤的放射疗法，越来越多地用于癌症治疗。对于宫颈癌和皮肤癌，它已成为100多年来的标准治疗方法，也是其他恶性肿瘤治疗指南的重要组成部分，包括头颈癌、皮肤癌、乳腺癌和前列腺癌。与外部放射治疗相比，近距离放射治疗有可能在短时间内将消融辐射剂量直接输送到改变的组织区域，其优点是剂量迅速下降，因此可以保留邻近器官。因此，患者能够更早地完成治疗，并且发生另一种癌症的风险低于常规放射治疗。近距离放射治疗作为根治性或姑息性治疗的使用越来越多，随着脉冲剂量率和高剂量率后负荷机的普及，近距放射治疗变得更加先进；新的3D/4D规划系统的使用进一步提高了治疗质量。本研究的目的是简要总结目前近距离放射治疗最常诊断的肿瘤的研究。本文提供的数据应该有助于特别是年轻的医生或物理学家探索和介绍近距离治疗癌症。
Cancer incidence and mortality depend on a number of factors, including age, socio-economic status and geographical location, and its prevalence is growing around the world. Most of cancer treatments include external beam radiotherapy or brachytherapy. Brachytherapy, a type of radiotherapy with energy from radionuclides inserted directly into the tumor, is increasingly used in cancer treatment. For cervical and skin cancers, it has become a standard therapy for more than 100 years as well as an important part of the treatment guidelines for other malignancies, including head and neck, skin, breast, and prostate cancers. Compared to external beam radiotherapy, brachytherapy has the potential to deliver an ablative radiation dose over a short period of time directly to the altered tissue area with the advantage of a rapid fall-off in dose, and consequently, sparing of adjacent organs. As a result, the patient is able to complete the treatment earlier, and the risks of occurrence of another cancer are lower than in conventional radiotherapy treatment. Brachytherapy has increased its use as a radical or palliative treatment, and become more advanced with the spread of pulsed-dose-rate and high-dose-rate afterloading machines; the use of new 3D/4D planning systems has additionally improved the quality of the treatment. The aim of the present study was to present short summaries of current studies on brachytherapy for the most frequently diagnosed tumors. Data presented in this manuscript should help especially young physicians or physicists to explore and introduce brachytherapy in cancer treatments.
登录
查看更多内容
影响因子：
1.9
作者：
Bartochowska, Anna;Wierzbicka, Malgorzata;Szyfter, Witold
通讯作者：
Szyfter, Witold
DOI：
10.1016/j.ijrobp.2009.11.002
发表时间：
2011-02-01
影响因子：
7
作者：
Georg, Petra;Lang, Stefan;Poetter, Richard
通讯作者：
Poetter, Richard
DOI：
10.1111/j.1754-9485.2012.02466.x
发表时间：
2013-04-01
影响因子：
1.6
作者：
Gauden, Ruth;Pracy, Martin;Gauden, Stan
通讯作者：
Gauden, Stan
影响因子：
5.7
作者：
Kovács, G;Pötter, R;Bertermann, H
通讯作者：
Bertermann, H
影响因子：
1.4
作者：
Kowalik L;Lyczek J;Sawicki M;Kazalski D
通讯作者：
Kazalski D