Development and Evaluation of a Perception Threshold Assessment System Using Non-contact Air Pressure Stimulation
Development and Evaluation of a Perception Threshold Assessment System Using Non-contact Air Pressure Stimulation
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使用非接触气压刺激的感知阈值评估系统的开发和评估
DOI：
10.11239/jsmbe.53.303
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发表时间：
2015
影响因子：
--
通讯作者：
瀬野 晋一郎
中科院分区：
文献类型：
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作者：
Mizuno Y;Hofer A;Fleischhacker WW;Uchida H;水野裕也，鈴木健文，Alex Hofer，W. Wolfgang Fleischhacker，櫻井準，新福正機，藤井和人，三村將，内田裕之;瀬野 晋一郎
许多定量的感觉测试方法已经开发出来用于评估周围神经功能，但这些测试设备需要电极接触或直接附着在体表上。因此，这是检测坏死或感染个体时的主要缺点。为了解决这一问题，我们开发了一种利用两种空气射流测量感官功能的新系统；稳定流动和脉动流动。该系统是一种简便、客观的检测皮肤表面感知阈值的方法。本研究的目的是评估新系统的准确性和实用性。通过用两种空气射流刺激皮肤表面，根据脉动动压[Pa]和定常流量[mL/s]计算感知阈值。本研究对24名健康志愿者（15名男性，9名女性，年龄在20-23岁）进行研究，并使用新系统测量感知阈值。右前臂对稳态流量和动压的感知阈值分别为51±20mL/s和285±282Pa。右中指指尖、左前臂和左中指指尖的稳定流速分别为58±33mL/s、56±15mL/s和62±26mL/s。同样，右中指尖、左前臂和左中指尖的动压力分别为392±225Pa、263±264Pa和399±190Pa。然而，对稳定流量和动压测量的感知阈值没有显示出显著的相关性。尽管许多问题仍有待解决，但这种新装置通过在距离喷嘴尖端适当距离（4mm至11mm）处刺激周围神经功能，可以有效地评估周围神经功能。需要在更大年龄范围的受试者和患者中进行进一步的研究，以提高测量感知阈值的灵敏度。
Many quantitative sensory testing methods have been developed for assessing peripheral nerve functions, but these testing devices require electrode contact or direct attachment on the body surface. Thus, this is the major disadvantage when testing individuals with necrosis or infection. To solve this problem, we developed a new system for the measurement of sensory function using two kinds of air jet; steady flow and pulsatile flow. This system is an easy and objective method for detecting the perception threshold without contact material on the skin surface. The purpose of this study was to evaluate the accuracy and utility of the new system. By stimulating the skin surface with two kinds of air jet, the perception threshold is calculated from the pulsatile dynamic pressure [Pa] and the steady flow [mL/s]. This study was performed on 24 healthy volunteers (15 males and 9 females, aged 20-23 years), and the perception threshold was measured using the new system. The perception thresholds for the steady flow and the dynamic pressure were 51±20mL/s and 285±282Pa, respectively, in the right forearm. The steady flows in the right middle finger tip, the left forearm and the left middle finger tip were 58±33mL/s, 56±15mL/s and 62±26mL/s, respectively. Similarly, the dynamic pressures in the right middle finger tip, the left forearm and the left middle finger tip were 392±225Pa, 263±264Pa and 399±190Pa, respectively. However, the perception thresholds measured against the steady flow and the dynamic pressure did not show a significant correlation. Although many issues remain to be solved, the new device is effective for assessing peripheral nerve function by stimulating at an appropriate distance (4mm to 11mm) from the tip of the nozzle. Further studies in subjects with a wide age range and in patients are required to improve the sensitivity of measuring the perception threshold.