Pleiotropic overdominance and the maintenance of genetic variation in polygenic characters.
Pleiotropic overdominance and the maintenance of genetic variation in polygenic characters.
复制标题
多效性过度显性和多基因性状遗传变异的维持。
DOI：
10.1093/genetics/107.2.321
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发表时间：
1984
期刊：
影响因子：
3.3
通讯作者：
J. Gillespie
中科院分区：
文献类型：
--
作者：
J. Gillespie
描述了一种选择模型，其中优化表型选择与多效性超显性相结合。因此，突变在表型进化模型中通常扮演的角色被平衡选择所取代。表型的平衡遗传变异和杂合性的表达式。近似分析的瞬态特性的模型表明，在某些情况下，行为是非常相似的模型的基础上的相互作用的突变和选择。
A model of selection is described in which optimizing phenotypic selection is combined with pleiotropic overdominance. Thus, the role that mutation commonly plays in models of phenotypic evolution is replaced by balancing selection. Expressions are provided for the equilibrium genetic variance in phenotype and for the heterozygosity. An approximate analysis of the transient properties of the model shows that, in certain circumstances, the behavior is quite similar to that of models based on the interaction of mutation and selection.