Theta Phase-Coordinated Memory Reactivation Reoccurs in a Slow-Oscillatory Rhythm during NREM Sleep

Theta Phase-Coordinated Memory Reactivation Reoccurs in a Slow-Oscillatory Rhythm during NREM Sleep
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NREM 睡眠期间,Theta 相位协调记忆重新激活以慢振荡节律重新发生

DOI:
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发表时间:
2017
期刊:
bioRxiv
影响因子:
--
通讯作者:
T. Staudigl
T. Staudigl
中科院分区:
--
文献类型:
--
作者:
T. Schreiner;Christian F. Doeller;O. Jensen;B. Rasch;T. Staudigl

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有人提出,睡眠对记忆巩固的贡献是重新激活先前编码的信息。为了阐明携带再激活相关助记信息的神经机制,我们研究了与清醒时记忆再激活相关的特定内容记忆特征是否会在随后的睡眠中重现。我们发现,不管生理状态如何,θ波振荡都能协调记忆的重新激活。睡眠期间的再激活模式以1hz的频率自动重新出现,表明通过缓慢的振荡活动进行协调。
It has been proposed that sleep’s contribution to memory consolidation is to reactivate prior encoded information. To elucidate the neural mechanisms carrying reactivation-related mnemonic information, we investigated whether content-specific memory signatures associated with memory reactivation during wakefulness reoccur during subsequent sleep. We show that theta oscillations orchestrate the reactivation of memories, irrespective of the physiological state. Reactivation patterns during sleep autonomously re-emerged at a rate of 1 Hz, indicating a coordination by slow oscillatory activity.
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