Wolbachia infection in Drosophila simulans: Does the female host bear a physiological cost?
Wolbachia infection in Drosophila simulans: Does the female host bear a physiological cost?
复制标题
DOI：
10.2307/2410971
复制
发表时间：
1997-02-01
期刊：
影响因子：
3.3
通讯作者：
Mercot, H
中科院分区：
文献类型：
--
作者：
Poinsot, D;Mercot, H
健身特性的三个果蝇simulans菌株感染的细胞内细菌属于沃尔巴克氏体属已与那些复制股票以前治愈感染的抗生素治疗。测量的性状是发育时间，卵到成虫的生存能力，卵孵化，生产力，繁殖力和功能卵巢的数量。第一菌株的个体被两种沃尔巴克氏体变体wHa和wNo双重感染。第2株为wHa感染株，第3株为wNo感染株。这里研究的沃尔巴克氏体引起细胞质不相容性（CI），当感染的雄性与未感染的雌性杂交时，胚胎死亡率高（70%至> 90%）。抗生素处理三代后，我们观察到所有菌株的生产力显着下降的治愈股票。这种下降不是由于抗生素毒性，而是与沃尔巴克氏体的损失有关。然而，在处理5代后，三个菌株中的两个菌株的效果消失了，在处理14代后进行的第三次测量中，在第三个菌株中没有发现这种效果。生产力差异的暂时性表明，沃尔巴克氏体不会提高感染菌株的生产力。另一方面，在所有测量的特征中，我们的结果显示Wolbachia对其宿主没有任何负面影响。当考虑沃尔巴克氏体的进化时，这可以解释，因为母系传播的寄生虫承受着强大的选择压力，不伤害雌性宿主。然而，CI将允许细菌即使在伤害女性时也能保持。这些沃尔巴克氏体引起的有害影响的明显缺乏可能是由于权衡，其中相对较低的细菌密度将通过抑制对雌性宿主的任何有害影响而有利于沃尔巴克氏体，代价是感染的较弱的母体传播率。
Fitness traits of three Drosophila simulans strains infected by endocellular bacteria belonging to the genus Wolbachia have been compared with those of replicate stocks previously cured from the infection by an antibiotic treatment. The traits measured were development time, egg-to-adult viability, egg hatch, productivity, fecundity, and the number of functional ovarioles. Individuals of the first strain were bi-infected by two Wolbachia variants, wHa and wNo. The second strain was infected by wHa, the third one by wNo. The Wolbachia studied here cause cytoplasmic incompatibility (CI), a high embryonic mortality (70% to > 90%) when an infected male is crossed with an uninfected female. Three generations after antibiotic treatment, we observed in all strains a significant drop in productivity in the cured stocks. This drop was not due to antibiotic toxicity and was associated with the loss of the Wolbachia. However the effect had disappeared in two of the three strains five generations after treatment, and could not be found in the third strain in a third measurement carried out 14 generations after treatment. The temporary nature of the productivity difference indicates that Wolbachia do not enhance productivity in infected strains. On the other hand, in all traits measured, our results show the absence of any negative effects of the Wolbachia on their host. This could be explained when considering Wolbachia evolution, as maternally transmitted parasites bear a strong selective pressure not to harm their female host. However, CI would allow the bacteria to be maintained even when harming the female. The apparent absence of deleterious effects caused by these Wolbachia might result from a trade-off, where a relatively low bacteria density would advantage the Wolbachia by suppressing any deleterious effects on the female host, at the cost of a weaker maternal transmission rate of the infection.