Experimental and computational infrared CD studies of prototypical peptide conformations.
Experimental and computational infrared CD studies of prototypical peptide conformations.
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原型肽构象的实验和计算红外 CD 研究。
DOI：
10.1021/bi00117a021
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发表时间：
1992
期刊：
影响因子：
2.9
通讯作者：
Diem,M
中科院分区：
文献类型：
--
作者：
Birke,SS;Agbaje,I;Diem,M
摘要：Yasui和Keiderling [Yasui， S. C., & Keiderling， T. A.(1986) bioolymers, 25, 5]报道了典型肽二级结构的红外振动圆二色性（VCD）光谱特征。这些结果表明，“随机线圈”肽构象显示的VCD信号近似于螺旋构象所显示的镜像特征。我们在此报告了观测到的VCD光谱与计算得到的几个二级结构的VCD光谱的比较，使用了以前用于计算模型VCD光谱的扩展耦合振荡形式
Revised Manuscript Received October 8, 1991 abstract: The infrared vibrational circular dichroism (VCD) spectral features of prototypical peptide secondary structures were reported previously by Yasui and Keiderling [Yasui, S. C., & Keiderling, T. A.(1986) Biopolymers 25, 5]. These results demonstrated that the “random coil” peptide conformation exhibits VCD signals which are approximately mirror-image features of those exhibited by-helical conformers. We report here a comparison of observed VCD spectra with those computed for several secondary structures, using the extended coupled oscillatorformalism employed previously to compute VCD spectra of model