A neurological complication of inferior petrosal sinus sampling during investigation for Cushing's disease: a case report.

A neurological complication of inferior petrosal sinus sampling during investigation for Cushing's disease: a case report.
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库欣病调查期间岩下窦取样的神经并发症:病例报告。

DOI:
10.1136/jnnp.62.5.527
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发表时间:
1997
期刊:
Journal of Neurology, Neurosurgery & Psychiatry
影响因子:
--
通讯作者:
W. J. Jeffcoate
W. J. Jeffcoate
中科院分区:
--
文献类型:
--
作者:
N. D. Sturrock;W. J. Jeffcoate

文献摘要

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一位45岁女性多毛症被发现有典型的促肾上腺皮质激素依赖性库欣病的生化特征,部分皮质醇抑制反应地塞米松。由于CT或MRI无法显示垂体腺瘤,因此她在可能的手术前进行了双侧同时岩下窦采样。在手术过程中,她发生了影响脑桥小脑连接处脑干的卒中。岩窦取样的这种并发症以前曾被描述过,但并没有被广泛认识;只有当微创检查的结果不确定时,才应进行该手术。
A 45 year old woman with hirsutism was found to have classic biochemical features of ACTH dependent Cushing's disease, with partial cortisol suppression in response to dexamethasone. As no pituitary adenoma could be visualised by CT or MRI, she proceeded to bilateral simultaneous inferior petrosal sinus sampling before possible surgery. During the course of this procedure she had a stroke affecting the brainstem at the level of the pontocerebellar junction. This complication of petrosal sinus sampling has been previously described but is not widely recognised; the procedure should only be undertaken when results of less invasive tests are equivocal.