Biocompatible, hyperbranched nanocarriers for the transport and release of copper ions.
Biocompatible, hyperbranched nanocarriers for the transport and release of copper ions.
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DOI：
10.1039/c4tb00454j
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发表时间：
2014-06
期刊：
影响因子：
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通讯作者：
Sabrina Nowag;Camille Frangville;Gerhard Multhaup;J. Marty;C. Mingotaud;Rainer Haag
中科院分区：
文献类型：
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作者：
Sabrina Nowag;Camille Frangville;Gerhard Multhaup;J. Marty;C. Mingotaud;Rainer Haag
设计了核-壳和核-多壳纳米载体来将铜离子输送到细胞内。在此，我们介绍了它们的合成和物理化学表征，并证明了它们的结构对铜的负载和释放有很大的影响。它们的低毒可能为平衡神经退行性疾病的铜稳态开辟了一条新的途径。
Core-shell and core-multishell nanocarriers were designed to transport copper ions into cells. Herein, we present their synthesis and physicochemical characterization and demonstrate the high influence of their architectures on the loading and release of copper. Their low toxicity may open a new way to balance the Cu-homeostasis in neurodegenerative diseases.