Pancreas stiffness in liver cirrhosis is an indicator of insulin secretion caused by portal hypertension and pancreatic congestion
Pancreas stiffness in liver cirrhosis is an indicator of insulin secretion caused by portal hypertension and pancreatic congestion
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DOI：
10.1111/hepr.13672
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发表时间：
2021-05
影响因子：
4.2
通讯作者：
Yoshiki Imamura;T. Kumagi;Taira Kuroda;M. Koizumi;O. Yoshida;Kozue Kanemitsu;F. Tada;Yoshinori Tanaka;M. Hirooka;Y. Hiasa
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文献类型：
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作者：
Yoshiki Imamura;T. Kumagi;Taira Kuroda;M. Koizumi;O. Yoshida;Kozue Kanemitsu;F. Tada;Yoshinori Tanaka;M. Hirooka;Y. Hiasa
门脉高压引起肝硬化患者胰腺充血和胰岛素分泌受损。然而，其发病机制尚不清楚，也没有成熟的无创成像方法来评估其发病机制。本研究的重点是胰腺硬度，通过剪切波弹性成像（SWE）评估，并检查其与门静脉高压和胰岛素分泌的关系。
Portal hypertension induces pancreatic congestion and impaired insulin secretion in patients with liver cirrhosis (LC). However, its mechanism is unclear, with no established noninvasive imaging method for the evaluation of its pathogeneses. The present study focused on pancreas stiffness, as assessed by shear wave elastography (SWE), and examined its association with portal hypertension and insulin secretion.