Modulation of synapse formation by cyclic adenosine monophosphate.
Modulation of synapse formation by cyclic adenosine monophosphate.
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环单磷酸腺苷调节突触形成。
DOI:
10.1126/science.6314503
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发表时间:
1983
期刊:
影响因子:
56.9
通讯作者:
M. Adler
中科院分区:
文献类型:
--
作者:
M. Nirenberg;S. Wilson;H. Higashida;A. Rotter;K. Krueger;N. Busis;R. Ray;J. Kenimer;M. Adler
Synapses between neuroblastoma-hybrid cells and myotubes exhibit a high degree of plasticity. Increase of cyclic adenosine monophosphate (AMP) levels of the hybrid cells for several days results in the appearance of functional voltage-sensitive Ca2+ channels, which are required for evoked secretion of acetylcholine. The results show that cyclic AMP regulates synaptogenesis by regulating the expression of voltage-sensitive Ca2+ channels, and suggest that cyclic AMP affects posttranslational modifications of some glycoproteins and cellular levels of certain proteins.
DOI:
--
发表时间:
1983
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Curtis,BM;Catterall,WA
通讯作者:
Catterall,WA
DOI:
--
发表时间:
1983
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Venter,JC;Fraser,CM;Schaber,JS;Jung,CY;Bolger,G;Triggle,DJ
通讯作者:
Triggle,DJ
DOI:
--
发表时间:
1981
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Weber,MJ
通讯作者:
Weber,MJ