Successful Treatment of Bacillary Hemoglobinuria in Japanese Black Cows
Successful Treatment of Bacillary Hemoglobinuria in Japanese Black Cows
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DOI：
10.1292/jvms.71.1105
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发表时间：
2009-08-01
影响因子：
1.2
通讯作者：
Deguchi, Eisaburo
中科院分区：
文献类型：
--
作者：
Takagi, Mitsuhiro;Yamato, Osamu;Deguchi, Eisaburo
在2003 ~ 2007年的不同时期，4头放养的日本黑牛表现出严重血红蛋白尿的主要临床症状。第一次就诊时的血液学分析显示严重贫血，生化分析显示严重溶血和肝功能破坏。虽然头2例患者死亡，但其余2例立即开始大剂量抗生素治疗的奶牛的血红蛋白尿和一般情况在3天内得到改善。采用聚合酶链式反应（PCR）对1头感染奶牛的血液样本进行了溶血梭菌检测。服用抗片形吸虫药后，再无血红蛋白尿病例。这些牛被诊断出患有细菌性血红蛋白尿，这是日本最早的几个病例。
Four pasture-fed Japanese Black cows showed the main clinical symptoms of severe hemoglobinuria at different periods between 2003 and 2007. Hematological analyses at the first consultation revealed severe anemia, and biochemical analyses indicated both severe hemolysis and disruption of hepatic function. Although the first 2 patients died, the hemoglobinuria and general condition of the remaining 2 cows, who were immediately initiated on large doses of antibiotics, improved within 3 days. Clostridium haemolyticum was detected by polymerase chain reaction (PCR) analysis of the blood sample of I of the infected cows. Anti-fascioliasis medicine is administered, and since then, no case of hemoglobinuria has been observed. The cows were diagnosed with bacillary hemoglobinuria, and they represent the first few cases in Japan.