Differences in applied electrical power between full thorax models and limited-domain models for RF cardiac ablation
Differences in applied electrical power between full thorax models and limited-domain models for RF cardiac ablation
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DOI：
10.1080/02656736.2020.1777330
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发表时间：
2020-01-01
影响因子：
3.1
通讯作者：
Berjano, Enrique
中科院分区：
文献类型：
--
作者：
Irastorza, Ramiro M.;Gonzalez-Suarez, Ana;Berjano, Enrique
目的：大多数射频心脏消融（RFCA）建模研究都是基于有限域模型，这意味着计算域仅限于有源电极周围几厘米的心肌和血液。当模拟恒定功率 RFCA 程序（例如心房颤动消融）时，重要的是要了解有源电极周围吸收了多少功率，以及在到达分散电极之前其余组织吸收了多少功率。方法：通过逐步合并具有简化几何形状的不同器官和组织（心室、心壁、皮下组织和皮肤、脊柱、肺和主动脉），建立3D胸部完整模型。其他二维有限域模型也是基于心肌和血液碎片构建的。解决了每个模型的电气问题，以估计有源电极周围的空间功率分布。结果：在全胸部模型中，当有源电极插入深度在0.5至2.5 mm之间时，79%至82%的功率被吸收在有源电极周围4 cm半径的球体中，而阻抗值范围为104至118 Ω，这与在4 cm半径圆柱形有限域模型中发现的阻抗值（83至103 Ω）一致。结论：有限域 RFCA 模型所施加的功率约为全胸腔模型所施加功率的 80%，相当于临床环境中设定的功率。
Purpose:Most modeling studies on radiofrequency cardiac ablation (RFCA) are based on limited-domain models, which means the computational domain is restricted to a few centimeters of myocardium and blood around the active electrode. When mimicking constant power RFCA procedures (e.g., atrial fibrillation ablation) it is important to know how much power is absorbed around the active electrode and how much in the rest of the tissues before reaching the dispersive electrode. Methods:3D thorax full models were built by progressively incorporating different organs and tissues with simplified geometries (cardiac chamber, cardiac wall, subcutaneous tissue and skin, spine, lungs and aorta). Other 2D limited-domain models were also built based on fragments of myocardium and blood. The electrical problem was solved for each model to estimate the spatial power distribution around the active electrode. Results:From 79 to 82% of the power was absorbed in a 4 cm-radius sphere around the active electrode in the full thorax model at active electrode insertion depths of between 0.5 and 2.5 mm, while the impedance values ranged from 104 to 118 omega, which were consistent with those found (from 83 to 103 omega) in a 4 cm radius cylindrical limited domain model. Conclusion:The applied power in limited-domain RFCA models is approximately 80% of that applied in full thorax models, which is equivalent to the power programed in a clinical setting.