Comparison of the family history method to direct interview. Factors affecting the diagnosis of depression.
Comparison of the family history method to direct interview. Factors affecting the diagnosis of depression.
复制标题
家族史方法与直接访谈的比较。
DOI：
10.1016/0165-0327(82)90019-2
复制
发表时间：
1982
影响因子：
6.6
通讯作者：
Kidd,KK
中科院分区：
文献类型：
--
作者：
Orvaschel,H;Thompson,WD;Belanger,A;Prusoff,BA;Kidd,KK
本研究比较了抑郁症的诊断信息，通过家庭病史报告和直接访谈获得的信息。从696个人的家庭成员的精神状况的报告，其中直接SADS-L采访也可获得。研究了受试者特征、治疗状态、抑郁症发病年龄和内源性症状对家族史报告的影响。还报告了家族史报告对抑郁症具体症状的敏感性和特异性。家族史报告诊断抑郁症的特异性一直很高，但敏感性因受试者和疾病特征而异。女性的敏感性略高于男性，先证者的敏感性明显高于其一级亲属和配偶。敏感性增加时，治疗，住院或内源性症状存在于主题，表明家族史报告是最准确的检测抑郁症的情况下。最后，抑郁症的症状，最不准确的亲属报告确定和修改抑郁症的家族史标准提出了建议。
This study compares information on the diagnosis of depression obtained by family history reports with the information obtained by direct interview. Reports were obtained from family memebers on the psychiatric status of 696 individuals for whom direct SADS-L interviews were also available. The effects on family history reports of subjects characteristics, treatment status, age of onset of depression, and endogenous symptoms were examined. Sensitivity and specificity for family history reports on the specific symptoms of depression are also reported. The specificity of family history reports for the diagnosis of depression was consistently high but sensitivity varied as a function of subject and illness characteristics. Sensitivity was somewhat higher for females than males and appreciably higher for probands than for their first-degree relatives and spouses. Sensitivity was increased whenever treatment, hospitalization or endogenous symptoms were present in the subject, indicating that family history reports are most accurate for detecting the cases of depression. Finally, the symptoms of depression that are least accurately reported by relatives are identified and suggestions for modifying the family history criteria for depression are proposed.