INSTRUMENTAL CONDITIONING OF JUGULAR SELF-INFUSION IN RHESUS MONKEY
INSTRUMENTAL CONDITIONING OF JUGULAR SELF-INFUSION IN RHESUS MONKEY
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DOI：
10.1126/science.133.3467.1829
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发表时间：
1961-01-01
期刊：
影响因子：
56.9
通讯作者：
SCHUSTER, CR
中科院分区：
文献类型：
--
作者：
CLARK, R;BRADY, JV;SCHUSTER, CR
描述了一种通过恒定留置颈静脉导管在恒河猴体内自体输注药剂溶液的技术。应用该技术的实验结果表明，以生理盐水自我注射为强化刺激，可对仪器杠杆反应进行条件化、熄灭、重整，并使其处于刺激控制和奖励计划控制之下。
A technique is described for self-infusion of pharmacologic agents in solution through a permanently indwelling jugular catheter in the rhesus monkey. The results of an experiment utilizing this technique demonstrate that an instrumental lever response can be conditioned, extinguished, reconditioned, and brought under stimulus control and reward-schedule control with saline self-infusion as the reinforcing stimulus.