Long-term control of recurrent anaplastic ependymoma with extracranial metastasis: Importance of multiple surgery and stereotactic radiosurgery procedures - Case report

Long-term control of recurrent anaplastic ependymoma with extracranial metastasis: Importance of multiple surgery and stereotactic radiosurgery procedures - Case report
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DOI:
10.2176/nmc.44.669
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发表时间:
2004-12-01
影响因子:
1.9
通讯作者:
Yoshimine, T
Yoshimine, T
中科院分区:
医学4区
文献类型:
--
作者:
Kinoshita, M;Izumoto, S;Yoshimine, T

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一名11岁的日本女孩因右额叶间变性室管膜瘤而住院。手术切除了肿瘤。然而,她在颈部淋巴结发生了继发性病变和颅外转移。在7年的时间里,她总共接受了8次颅内肿瘤切除手术,5次有6个靶点的立体定向放射手术和5次颈部淋巴结切除手术。她目前活得很好,生活质量很好,除了右侧面神经麻痹外,没有主要的神经功能缺陷。手术与放疗相结合可达到间变性室管膜瘤的局部控制。如果肿瘤不涉及关键结构,即使发生颅外转移,多次手术或放射手术也能获得良好的结果。
An 11-year-old Japanese girl presented with a right frontal lobe anaplastic ependymoma. The tumor was removed surgically. However, she developed a secondary lesion and extracranial metastasis in the cervical lymph node. In total, she underwent eight intracranial tumor removal procedures, five stereotactic radiosurgeries with six targets, and five cervical lymph node removal surgeries during the course of 7 years. She is currently alive with a good quality of life, and has no major neurological deficits except right facial nerve palsy. The combination of surgery and radiosurgery can achieve local control of anaplastic ependymoma. Multiple surgery or radiosurgery procedures can result in good outcome, if the tumor does not involve crucial structures, even if extracranial metastasis occurs.