Higher-order social cognition in first-episode major depression
Higher-order social cognition in first-episode major depression
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DOI：
10.1016/j.psychres.2013.12.010
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发表时间：
2014-04-30
影响因子：
11.3
通讯作者：
Lysaker, Paul H.
中科院分区：
文献类型：
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作者：
Ladegaard, Nicolai;Larsen, Erik Roj;Lysaker, Paul H.
患有重性抑郁症的患者在多个认知能力方面经历困难。越来越多的研究将情感障碍与社会认知异常联系起来，特别是与离散情绪刺激的处理联系起来。然而，很少有人探讨可能损害高阶社会认知，包括心理理论，社会知觉和元认知。44例首次发作的单相抑郁症患者和相同数量的匹配对照组进行了评估的元认知评估量表（MAS-A），第五-Happe动画（FHA）和社会推理的意识测试（TASIT）。此外，神经认知评估采用剑桥神经心理测试自动电池（CANTAB）。抑郁症患者在所有高阶社会认知能力领域都表现出障碍。重要的是，在控制了可能的协变量（包括神经认知）后，社会认知变量保持了组间显著性。结果表明，首发抑郁症患者在高阶社会认知的所有领域，包括心理理论，社会知觉和元认知的经验困难。(C)2014爱思唯尔爱尔兰有限公司版权所有。
Patients suffering from major depression experience difficulties in multiple cognitive faculties. A growing body of research has linked affective disorders to abnormalities in social cognition and specifically the processing of discrete emotional stimuli. However, little inquiry has gone into possible impairment in higher-order social cognition including theory of mind, social perception and metacognition. Forty-four medication-naive patients with first-episode unipolar major depressive disorder and an equal number of matched controls were assessed by the Metacognitive Assessment Scale-Abbreviated (MAS-A), The Frith-Happe animations (FHA) and The Awareness of Social Inference Test (TASIT). Additionally, neurocognition was assessed utilyzing the Cambridge Neuropsychological Test Automated Battery (CANTAB). Depressed patients showed impairment in all domains of higher-order social cognitive ability. Importantly, social cognitive variables retained their inter-group significance after controlling for possible covariates including neurocognition. Results indicate that first-episode depressed patients experience difficulties in all domains of higher-order social cognition including theory of mind, social perception and metacognition. (C) 2014 Elsevier Ireland Ltd. All rights reserved.