Ordino: a visual cancer analysis tool for ranking and exploring genes, cell lines and tissue samples

Ordino: a visual cancer analysis tool for ranking and exploring genes, cell lines and tissue samples
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DOI:
10.1093/bioinformatics/btz009
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发表时间:
2019-01
期刊:
影响因子:
5.8
通讯作者:
M. Streit;S. Gratzl;Holger Stitz;Andreas Wernitznig;T. Zichner;C. Haslinger
M. Streit;S. Gratzl;Holger Stitz;Andreas Wernitznig;T. Zichner;C. Haslinger
中科院分区:
生物学3区
文献类型:
--
作者:
M. Streit;S. Gratzl;Holger Stitz;Andreas Wernitznig;T. Zichner;C. Haslinger

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摘要 摘要 Ordino 是一种基于网络的癌症基因组学分析工具,允许用户根据预加载的数据(包括癌症基因组图谱、癌细胞系百科全书和手动上传的信息)灵活排序、过滤和探索基因、细胞系和组织样本。交互式表格数据可视化促进了用户驱动的优先级划分过程,形成了 Ordino 的核心组件。所选项目的详细视图补充了探索。可以通过集成的会话管理来存储、共享和复制调查结果。可用性和实施​​ Ordino 可在 https://ordino.caleydoapp.org 上公开获取。源代码根据 Mozilla 公共许可证 2.0 在 https://github.com/Caleydo/ordino 发布。补充信息 补充数据可在生物信息学在线获取。
Abstract Summary Ordino is a web-based analysis tool for cancer genomics that allows users to flexibly rank, filter and explore genes, cell lines and tissue samples based on pre-loaded data, including The Cancer Genome Atlas, the Cancer Cell Line Encyclopedia and manually uploaded information. Interactive tabular data visualization that facilitates the user-driven prioritization process forms a core component of Ordino. Detail views of selected items complement the exploration. Findings can be stored, shared and reproduced via the integrated session management. Availability and implementation Ordino is publicly available at https://ordino.caleydoapp.org. The source code is released at https://github.com/Caleydo/ordino under the Mozilla Public License 2.0. Supplementary information Supplementary data are available at Bioinformatics online.