The Role of Pathogen-Secreted Proteins in Fungal Vascular Wilt Diseases.
The Role of Pathogen-Secreted Proteins in Fungal Vascular Wilt Diseases.
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DOI：
10.3390/ijms161023970
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发表时间：
2015-10-09
影响因子：
5.6
通讯作者：
Rep M
中科院分区：
文献类型：
--
作者：
de Sain M;Rep M
有限数量的真菌可通过定殖于维管系统而在植物中引起萎蔫病，最知名的是大丽轮枝菌（Verticillium dahliae）和尖孢镰刀菌（Fusarium oxysporum）。与所有病原微生物一样，维管萎蔫真菌在宿主定殖期间分泌蛋白质。全基因组测序和蛋白质组学筛选已经鉴定了许多这些蛋白质，包括小的，通常富含半胱氨酸的蛋白质，坏死诱导蛋白质和酶。基因缺失实验已经提供了证据表明，这些蛋白质中的一些是致病性所需的，而其他分泌蛋白质的作用仍然是谜。另一方面，植物免疫系统可以识别一些分泌的蛋白质或它们的作用，从而产生抗病性。我们给出了一个概述，目前已知的蛋白质分泌的维管枯萎真菌，并讨论其在致病性和植物免疫中的作用。
A limited number of fungi can cause wilting disease in plants through colonization of the vascular system, the most well-known being Verticillium dahliae and Fusarium oxysporum. Like all pathogenic microorganisms, vascular wilt fungi secrete proteins during host colonization. Whole-genome sequencing and proteomics screens have identified many of these proteins, including small, usually cysteine-rich proteins, necrosis-inducing proteins and enzymes. Gene deletion experiments have provided evidence that some of these proteins are required for pathogenicity, while the role of other secreted proteins remains enigmatic. On the other hand, the plant immune system can recognize some secreted proteins or their actions, resulting in disease resistance. We give an overview of proteins currently known to be secreted by vascular wilt fungi and discuss their role in pathogenicity and plant immunity.