A RECEPTOR KINASE-LIKE PROTEIN ENCODED BY THE RICE DISEASE RESISTANCE GENE, XA21

A RECEPTOR KINASE-LIKE PROTEIN ENCODED BY THE RICE DISEASE RESISTANCE GENE, XA21
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DOI:
10.1126/science.270.5243.1804
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发表时间:
1995-12-15
期刊:
影响因子:
56.9
通讯作者:
RONALD, P
RONALD, P
中科院分区:
综合性期刊1区
文献类型:
--
作者:
SONG, WY;WANG, GL;RONALD, P

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水稻Xa 21基因,赋予对黄单胞菌的抗性。通过定位克隆法分离到一个新的小球藻6号。50株转Xa 21基因水稻植株表现出高水平的抗病性。预测的蛋白质,它携带富含亮氨酸的重复基序和丝氨酸-苏氨酸激酶样结构域的序列,表明在细胞表面识别的病原体配体和随后的细胞内防御反应的激活的作用。Xa 21的特性将有助于理解植物抗病性,并导致水稻的工程抗性。
The rice Xa21 gene, which confers resistance to Xanthomonas oryzae pv. oryzae race 6, was isolated by positional cloning. Fifty transgenic rice plants carrying the cloned Xa21 gene display high levels of resistance to the pathogen. The sequence of the predicted protein, which carries both a leucine-rich repeat motif and a serine-threonine kinase-like domain, suggests a role in cell surface recognition of a pathogen ligand and subsequent activation of an intracellular defense response. Characterization of Xa21 should facilitate understanding of plant disease resistance and lead to engineered resistance in rice.